BIG4BIO: Mapping America's Life Science Ecosystems

Inside the Regional Clusters That Power the Biotechnology Industry

Geography shapes science more than the industry typically admits. BIG4BIO: Mapping America's Life Science Ecosystems is the first panoramic portrait of the eight American cities where modern medicine is being made — and an argument that place matters more than the industry has recognized.
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Eight regions. Eight personalities. One industry.

The eight personality lines

  • The Bay Area invents.
  • Boston translates.
  • San Diego collaborates.
  • Philadelphia leads the world in cell and gene therapy.
  • New York capitalizes.
  • Los Angeles imagines.
  • Seattle computes.
  • The Capital Region sets the rules.

From the book

"Modern biotechnology looks like a global industry. In reality, it runs on ecosystems. From the laboratories of Boston to the venture-funded startups of the San Francisco Bay Area, life science innovation emerges from regional clusters where science, capital, and institutions converge. These ecosystems shape how discoveries become companies, therapies, and industries — and they are the most important thing about the industry that most people have never thought about."

About The Author

Tilton Little has spent more than twenty years observing and reporting on the American life science industry, covering eight of the country's most important regional clusters. He is the founder of Big4Bio and CEO of BigBio Communications.
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