Inside the regional clusters that power the biotechnology industry. Geography shapes science more than the industry typically admits. BIG4BIO: Mapping America’s Life Science Ecosystems is the first panoramic portrait of the eight American cities where modern medicine is being made, and an argument that place matters more than the industry has recognized. Now available in hardcover, paperback, and eBook.

“Modern biotechnology looks like a global industry. In reality, it runs on ecosystems. From the laboratories of Boston to the venture-funded startups of the San Francisco Bay Area, life science innovation emerges from regional clusters where science, capital, and institutions converge. These ecosystems shape how discoveries become companies, therapies, and industries — and they are the most important thing about the industry that most people have never thought about.”

Tilton Little has spent more than twenty years observing and reporting on the American life science industry, covering eight of the country’s most important regional clusters. He is the founder of Big4Bio and CEO of BigBio Communications.